This study was performed to determine the hypolipidaemic effects of Allium tuberosum Rottl. (ATR), fermented Allium tuberosum Rottl. (FATR) and processed sulfur. Thirty male Wistar rats were divided into five groups: (i) CON (control, normal diet); (ii) HFD (high fat diet); (iii) HS (HFD+processed sulfur); (iv) AS (HFD+ATR+processed sulfur) and (v) FAS (HFD+FATR+ processed sulfur). Animals were fed the diets for six weeks. Body weights of the animals were recorded in the beginning and end of experiment. The animals were sacrificed, organ and tissue weights recorded and blood and liver samples were analyzed for various biochemical parameters. Body weight gain in the AS group was significantly (p<0.05) lower than the other groups. Spleen and kidney weights in FAS group were significantly (p<0.05) higher than the other groups. The weight of epididymal adipose tissue in AS group was significantly (p<0.05) lower than that of HFD group. The weight of retroperitoneal fat in HFD groups was significantly (p<0.05) higher than other groups. The concentration of aspartate amino transferase (AST) was significantly (p<0.05) higher in HFD group compared to HS, AS and FAS groups. Total liver lipid contents in the HFD group was significantly (p<0.05) higher than the other groups. AS and FAS group rats had significantly (p<0.05) lower triglyceride and total cholesterol compared to HFD group. All together, these results suggest that FATR and processed sulfur may play an important role in reducing body fat deposition and altering the serum and liver lipid profile in rats.
Eun-Jeong Son, Uttam Kumar Pal, Prabhat Kumar Mandal, Go-Eun Hong, Soo-Ki Kim and Chi-Ho Lee, 2012. Hypolipidaemic Effect of Processed Sulfur, Allium tuberosum Rottl. and Fermented Allium tuberosum Rottl. in Rat. Asian Journal of Animal and Veterinary Advances, 7: 812-821.